Nitric Oxide: Basic Regulations and Pharmacological Interventions

5th International Symposium organized by Nitric Oxide Club, Slovak Physiological Society and Institute of Normal and Pathological Physiology, Slovak Academy of Sciences

September 19-24, 2007
Tučepi, Croatia

The nitric oxide produced by mammalian cells at an appropriate magnitude and timing may serve as a key signaling molecule in physiological processes as diverse as cardiovascular regulation, neuronal communication and host-defense. On the other hand, excessive and unregulated NO synthesis has been implicated as causal or contributing to pathophysiological conditions including many lethal and debilitating diseases of humans. The organizers are convinced that the Symposium will contribute at obtaining new knowledge or insights into the role of the NO in physiological regulatory processes of CVD and CNS disorders.

We all are well aware of the fact that the cardiovascular disease is the main
cause of death in the European Union. CVD accounts for 42% (over 1.9 million) of all deaths each year in the EU 25. More than 27% of the adult EU population aged 18-65 (83 million people) is estimated to experience at least one form of mental disorder during any given year. The economical impact of CVD and mental ill health (MIH) is immense. In the EU 25 the total bill for CVD was estimated to be Euro 169 billion a year (2003), the total annual cost for the year 2004 for MIH was estimated at Euro 240 billion.

CVD and MIH have multiple causes. CVD can affect the mental health of patients and MIH is as much a risk factor for CVD and mortality as lack of physical activity and high cholesterol. CVD and MIH are associated with working and living conditions, individual characteristics and socio-economical status. A strong influence exerts the lifestyle-related behaviours. Many individuals need to change their lifestyles in order to protect and improve their health. The well-being of individuals depends on their relevant physiological regulatory mechanisms. We need to understand them in order to formulate programmes to help people to cope with every-day loads and improve their quality of life. This is the reason why this Symposium is aimed to contribute also to activities of the European Network for Workplace Health Promotion.

If you would like to attend please contact:

Dr. Fedor Jagla
Institute of Normal and Pathological Physiology
Slovak Academy of Sciences
Sienkiewiczova 1
813 71 Bratislava
Slovak Republic

Phone: +421 (0) 2 52926618
Fax: +421 2 52 96 85 16
E-mail: Fedor.Jagla@savba.sk